Source of Core Ingredients for Sepiwhite MSH

Sepiwhite MSH is a trade name for a cosmetic skin-brightening active developed by Seppic (Air Liquide Healthcare/Seppic). Its INCI name is Undecylenoyl Phenylalanine.

The core molecule is produced by chemically combining two main components:

Component	Source / origin	Role
Phenylalanine	Amino-acid feedstock, commonly manufactured by fermentation	Provides the phenylalanine portion of the molecule
Undecylenoyl group	Derived from undecylenic acid, an unsaturated fatty acid traditionally obtained from castor-oil processing	Provides the lipophilic fatty-acid portion
Sepiwhite MSH	Chemical derivative synthesized from these building blocks	Cosmetic active targeting hyperpigmentation

Source of Core Ingredients for Sepiwhite MSH

1. Phenylalanine component

Phenylalanine is an aromatic amino acid. In Sepiwhite MSH, it is incorporated into the active molecule rather than being present simply as free phenylalanine.

The resulting compound is N-undecylenoyl-L-phenylalanine, also called Undecylenoyl Phenylalanine, CAS 175357-18-3. The FDA substance database confirms this chemical identity.

2. Undecylenoyl component

The other structural portion is the undecylenoyl fatty-acid-derived chain. This lipophilic portion is attached to phenylalanine to produce the amphiphilic/lipoamino-acid structure.

Thus, Sepiwhite MSH is not a mixture of phenylalanine + an α-MSH peptide. Rather, its principal active is one chemically defined lipoamino-acid molecule: Undecylenoyl Phenylalanine.

3. Natural-origin status

Seppic describes Sepiwhite MSH as 100% natural and reports a NOC (ISO 16128) >99% designation. It is also listed as COSMOS approved, Halal certified and suitable for vegan formulations.

A Japanese supplier document likewise describes the QD version as 100% plant-derived and identifies the INCI as Undecylenoyl Phenylalanine.

4. Important distinction

Sepiwhite MSH → core active → Undecylenoyl Phenylalanine

It is therefore more accurate to describe its raw-material origin as:

plant/naturally derived fatty-acid component + phenylalanine-derived amino-acid component → lipoamino acid Undecylenoyl Phenylalanine.

The commercial Sepiwhite MSH material supplied by Seppic is essentially this active ingredient; Seppic lists Undecylenoyl Phenylalanine as the INCI and recommends approximately 2% use level for the standard MSH grade.

Note: The exact botanical sources, feedstocks, and manufacturing route used for each starting raw material are proprietary; publicly available Seppic information does not specify a particular plant species as the source of the phenylalanine or undecylenic-acid feedstock.

From cellsbio health technology co.,ltd

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